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Structure paper

TitleStructural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.
Journal, issue, pagesEMBO J., Vol. 36, Page 2251-2262, Year 2017
Publish dateFeb 6, 2017 (structure data deposition date)
AuthorsMcGrath, D.A. / Fifield, B.A. / Marceau, A.H. / Tripathi, S. / Porter, L.A. / Rubin, S.M.
External linksEMBO J. / PubMed:28666995
MethodsX-ray diffraction
Resolution2.7 - 3.6 Å
Structure data

PDB-5uq1:
Crystal structure of human Cdk2-Spy1 complex
Method: X-RAY DIFFRACTION / Resolution: 3.201 Å

PDB-5uq2:
Crystal structure of human Cdk2-Spy1 complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5uq3:
Crystal structure of human Cdk2-Spy1-P27 ternary complex
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/CELL CYCLE / phosphotransferase / protein kinase / cell cycle regulation / TRANSFERASE-CELL CYCLE complex / Transferase/Transferase Inhibitor / Transferase-Transferase Inhibitor complex

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