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| Title | A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 292, Page 14706-14717, Year 2017 |
| Publish date | Apr 26, 2017 (structure data deposition date) |
Authors | De Nardis, C. / Hendriks, L.J.A. / Poirier, E. / Arvinte, T. / Gros, P. / Bakker, A.B.H. / de Kruif, J. |
External links | J. Biol. Chem. / PubMed:28655766 |
| Methods | X-ray diffraction |
| Resolution | 2.22 - 2.3 Å |
| Structure data | ![]() PDB-5nsc: ![]() PDB-5nsg: |
| Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-ZN: ![]() ChemComp-ACT: |
| Source |
|
Keywords | IMMUNE SYSTEM / IgG / Fc heterodimer / L351D/L368E + L351K/T366K / Fc homodimer / L351D/L368E + L351D/L368E |
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homo sapiens (human)
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