+Search query
-Structure paper
Title | A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 292, Page 14706-14717, Year 2017 |
Publish date | Apr 26, 2017 (structure data deposition date) |
Authors | De Nardis, C. / Hendriks, L.J.A. / Poirier, E. / Arvinte, T. / Gros, P. / Bakker, A.B.H. / de Kruif, J. |
External links | J. Biol. Chem. / PubMed:28655766 |
Methods | X-ray diffraction |
Resolution | 2.22 - 2.3 Å |
Structure data | PDB-5nsc: PDB-5nsg: |
Chemicals | ChemComp-GOL: ChemComp-HOH: ChemComp-ZN: ChemComp-ACT: |
Source |
|
Keywords | IMMUNE SYSTEM / IgG / Fc heterodimer / L351D/L368E + L351K/T366K / Fc homodimer / L351D/L368E + L351D/L368E |