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TitleGreen mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 7154-7159, Year 2017
Publish dateOct 19, 2016 (structure data deposition date)
AuthorsCiolek, J. / Reinfrank, H. / Quinton, L. / Viengchareun, S. / Stura, E.A. / Vera, L. / Sigismeau, S. / Mouillac, B. / Orcel, H. / Peigneur, S. ...Ciolek, J. / Reinfrank, H. / Quinton, L. / Viengchareun, S. / Stura, E.A. / Vera, L. / Sigismeau, S. / Mouillac, B. / Orcel, H. / Peigneur, S. / Tytgat, J. / Droctove, L. / Beau, F. / Nevoux, J. / Lombes, M. / Mourier, G. / De Pauw, E. / Servent, D. / Mendre, C. / Witzgall, R. / Gilles, N.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28630289
MethodsX-ray diffraction
Resolution1.06 Å
Structure data

PDB-5m4v:
X-ray structure of the mambaquaretin-1, a selective antagonist of the vasopressin type 2 receptor
Method: X-RAY DIFFRACTION / Resolution: 1.06 Å

Chemicals

ChemComp-PGO:
S-1,2-PROPANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • dendroaspis angusticeps (eastern green mamba)
KeywordsTOXIN / Vasopressin antagonist / mamba venom / kunitz

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