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-Structure paper
Title | Expanding the Scope of Electrophiles Capable of Targeting K-Ras Oncogenes. |
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Journal, issue, pages | Biochemistry, Vol. 56, Page 3178-3183, Year 2017 |
Publish date | Mar 17, 2017 (structure data deposition date) |
Authors | McGregor, L.M. / Jenkins, M.L. / Kerwin, C. / Burke, J.E. / Shokat, K.M. |
External links | Biochemistry / PubMed:28621541 |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.72 Å |
Structure data | PDB-5v6s: PDB-5v6v: |
Chemicals | ChemComp-GDP: ChemComp-MG: ChemComp-8YD: ChemComp-HOH: ChemComp-CA: ChemComp-8YA: ChemComp-GOL: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / K-Ras G12C / covalent inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex |