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TitleAn alternative conformation of ER beta bound to estradiol reveals H12 in a stable antagonist position.
Journal, issue, pagesSci Rep, Vol. 7, Page 3509-3509, Year 2017
Publish dateOct 17, 2016 (structure data deposition date)
AuthorsSouza, P.C.T. / Textor, L.C. / Melo, D.C. / Nascimento, A.S. / Skaf, M.S. / Polikarpov, I.
External linksSci Rep / PubMed:28615710
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5toa:
Crystal Structure of ER beta bound to Estradiol
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Estrogen receptor / estradiol / Helix 12 / agonist

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