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TitleTight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 56, Page 10592-10597, Year 2017
Publish dateMar 2, 2017 (structure data deposition date)
AuthorsEichinger, A. / Neumaier, I. / Pschenitza, M. / Niessner, R. / Knopp, D. / Skerra, A.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:28603847
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5nbw:
Crystal structure of the Fab fragment 22F12 in complex with 3-hydroxybenzo[a]pyrene
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-8SK:
benzo[a]pyren-3-ol

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antibody / benzo[a]pyrene / Fab fragment / hapten

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