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Structure paper

TitleShigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.
Journal, issue, pagesGut Microbes, Vol. 8, Page 544-560, Year 2017
Publish dateMar 31, 2016 (structure data deposition date)
AuthorsMaldonado-Contreras, A. / Birtley, J.R. / Boll, E. / Zhao, Y. / Mumy, K.L. / Toscano, J. / Ayehunie, S. / Reinecker, H.C. / Stern, L.J. / McCormick, B.A.
External linksGut Microbes / PubMed:28598765
MethodsX-ray diffraction
Resolution2.912 Å
Structure data

PDB-5j44:
Crystal structure of the Secreted Extracellular protein A (SepA) from Shigella flexneri
Method: X-RAY DIFFRACTION / Resolution: 2.912 Å

Chemicals

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • shigella flexneri (bacteria)
KeywordsHYDROLASE / Protease / Beta-helix / Secreted

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