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| Title | A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases. |
|---|---|
| Journal, issue, pages | Sci Rep, Vol. 7, Page 2648-2648, Year 2017 |
| Publish date | Nov 10, 2016 (structure data deposition date) |
Authors | Buey, R.M. / Fernandez-Justel, D. / Marcos-Alcalde, I. / Winter, G. / Gomez-Puertas, P. / de Pereda, J.M. / Luis Revuelta, J. |
External links | Sci Rep / PubMed:28572600 |
| Methods | X-ray diffraction |
| Resolution | 2.4 - 2.462 Å |
| Structure data | ![]() PDB-5mcp: ![]() PDB-5tc3: |
| Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-5GP: ![]() ChemComp-GDP: ![]() ChemComp-ACT: |
| Source |
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Keywords | OXIDOREDUCTASE / IMP dehydrogenase / Ashbya gossypii / allosteric modulator / purine nucleotides |
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ashbya gossypii (strain atcc 10895 / cbs 109.51 / fgsc 9923 / nrrl y-1056) (fungus)
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