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Structure paper

TitleStructural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 24, Page 578-587, Year 2017
Publish dateDec 13, 2016 (structure data deposition date)
AuthorsNomura, K. / Klejnot, M. / Kowalczyk, D. / Hock, A.K. / Sibbet, G.J. / Vousden, K.H. / Huang, D.T.
External linksNat. Struct. Mol. Biol. / PubMed:28553961
MethodsX-ray diffraction
Resolution2.16 Å
Structure data

PDB-5mnj:
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / Ubiquitin ligase

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