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TitleInosine Can Increase DNA's Susceptibility to Photo-oxidation by a Ru II Complex due to Structural Change in the Minor Groove.
Journal, issue, pagesChemistry, Vol. 23, Page 10344-10351, Year 2017
Publish dateJun 1, 2014 (structure data deposition date)
AuthorsKeane, P.M. / Hall, J.P. / Poynton, F.E. / Poulsen, B.C. / Gurung, S.P. / Clark, I.P. / Sazanovich, I.V. / Towrie, M. / Gunnlaugsson, T. / Quinn, S.J. ...Keane, P.M. / Hall, J.P. / Poynton, F.E. / Poulsen, B.C. / Gurung, S.P. / Clark, I.P. / Sazanovich, I.V. / Towrie, M. / Gunnlaugsson, T. / Quinn, S.J. / Cardin, C.J. / Kelly, J.M.
External linksChemistry / PubMed:28543779
MethodsX-ray diffraction
Resolution0.95 - 1.39 Å
Structure data

PDB-4qio:
Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCGGCGCCIA) at high resolution
Method: X-RAY DIFFRACTION / Resolution: 0.95 Å

PDB-5et2:
Lambda-Ru(TAP)2(dppz)]2+ bound to d(TTGGCGCCAA)
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

Chemicals

ChemComp-BA:
Unknown entry

ChemComp-RKL:
Ru(tap)2(dppz) complex

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsDNA / intercalation / ruthenium complex / inosine / Ruthenium Intercalation DNA Photoactive

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