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TitleMechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E4539-E4548, Year 2017
Publish dateMay 1, 2017 (structure data deposition date)
AuthorsJeong, H. / Park, J. / Kim, H.I. / Lee, M. / Ko, Y.J. / Lee, S. / Jun, Y. / Lee, C.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28533415
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5xjg:
Crystal structure of Vac8p bound to Nvj1p
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-PE5:
3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL / precipitant*YM

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsSIGNALING PROTEIN/MEMBRANE PROTEIN / Vac8p / Nvj1p / Membrane contact site / Nucleus-vacuole junction / SIGNALING PROTEIN-MEMBRANE PROTEIN complex

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