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Structure paper

TitleStructural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Journal, issue, pagesMol. Cell, Vol. 66, Page 711-720.e3, Year 2017
Publish dateMay 23, 2016 (structure data deposition date)
AuthorsHashimoto, H. / Wang, D. / Horton, J.R. / Zhang, X. / Corces, V.G. / Cheng, X.
External linksMol. Cell / PubMed:28529057
MethodsX-ray diffraction
Resolution1.744 - 3.199 Å
Structure data

PDB-5k5h:
Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 3.108 Å

PDB-5k5i:
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P65
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

PDB-5k5j:
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212
Method: X-RAY DIFFRACTION / Resolution: 2.287 Å

PDB-5k5l:
Homo sapiens CCCTC-binding factor (CTCF) ZnF6-8 and H19 sequence DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 3.125 Å

PDB-5kkq:
Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 1.744 Å

PDB-5t00:
Human CTCF ZnF3-7 and methylated DNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

PDB-5t0u:
CTCF ZnF2-7 and DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 3.199 Å

PDB-5und:
Crystal Structure of CTCF(ZnF 4-10) With 28-mer DNA
Method: X-RAY DIFFRACTION / Resolution: 2.549 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSCRIPTION/DNA / CCCTC-binding factor / CTCF / zinc finger / TRANSCRIPTION-DNA complex / TRANSCRIPTION REGULATOR/DNA / TRANSCRIPTION REGULATOR-DNA complex / transcription factor zinc finger protein-DNA binding insulator/chromatin architecture

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