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TitleMetal Ions Effectively Ablate the Action of Botulinum Neurotoxin A.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 139, Page 7264-7272, Year 2017
Publish dateApr 11, 2017 (structure data deposition date)
AuthorsBremer, P.T. / Pellett, S. / Carolan, J.P. / Tepp, W.H. / Eubanks, L.M. / Allen, K.N. / Johnson, E.A. / Janda, K.D.
External linksJ. Am. Chem. Soc. / PubMed:28475321
MethodsX-ray diffraction
Resolution2.15 - 2.6 Å
Structure data

PDB-5vgv:
Structure of the C. botulinum neurotoxin serotype A with Cu bound
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-5vgx:
Structure of the C. botulinum neurotoxin serotype A with Hg bound
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-CU:
COPPER (II) ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-HG:
Unknown entry

Source
  • clostridium botulinum (bacteria)
KeywordsTOXIN / botulinum / neurotoxin / metalloprotease

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