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Structure paper

TitleThe Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Journal, issue, pagesSci Rep, Vol. 7, Page 1424-1424, Year 2017
Publish dateDec 11, 2017 (structure data deposition date)
AuthorsJoshi, S. / Chen, L. / Winter, M.B. / Lin, Y.L. / Yang, Y. / Shapovalova, M. / Smith, P.M. / Liu, C. / Li, F. / LeBeau, A.M.
External linksSci Rep / PubMed:28465619
MethodsX-ray diffraction
Resolution1.86 - 2.2 Å
Structure data

PDB-6buy:
Crystal structure of porcine aminopeptidase-N with Glycine
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6bv0:
Crystal structure of porcine aminopeptidase-N with Arginine
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

PDB-6bv1:
Crystal structure of porcine aminopeptidase-N with Aspartic acid
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6bv2:
Crystal structure of porcine aminopeptidase-N with Isoleucine
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

PDB-6bv3:
Crystal structure of porcine aminopeptidase-N with Leucine
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6bv4:
Crystal structure of porcine aminopeptidase-N with Methionine
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GLY:
GLYCINE

ChemComp-SO4:
SULFATE ION

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ARG:
ARGININE

ChemComp-ASP:
ASPARTIC ACID

ChemComp-ILE:
ISOLEUCINE

ChemComp-LEU:
LEUCINE

ChemComp-MET:
METHIONINE

Source
  • sus scrofa (pig)
KeywordsHYDROLASE / ZINC AMINOPEPTIDASE

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