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TitleThe Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I).
Journal, issue, pagesAntioxid. Redox Signal., Vol. 27, Page 1491-1504, Year 2017
Publish dateJun 3, 2017 (structure data deposition date)
AuthorsSalinas, G. / Gao, W. / Wang, Y. / Bonilla, M. / Yu, L. / Novikov, A. / Virginio, V.G. / Ferreira, H.B. / Vieites, M. / Gladyshev, V.N. ...Salinas, G. / Gao, W. / Wang, Y. / Bonilla, M. / Yu, L. / Novikov, A. / Virginio, V.G. / Ferreira, H.B. / Vieites, M. / Gladyshev, V.N. / Gambino, D. / Dai, S.
External linksAntioxid. Redox Signal. / PubMed:28463568
MethodsX-ray diffraction
Resolution2.7 - 2.88 Å
Structure data

PDB-5w1j:
Echinococcus granulosus thioredoxin glutathione reductas (egTGR)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5w1l:
Echinococcus granulosus thioredoxin glutathione reductas (egTGR) with Gold
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-AU:
Unknown entry

Source
  • echinococcus granulosus (invertebrata)
KeywordsSIGNALING PROTEIN / egTGR / redox / ntioxidant / antioxidant

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