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TitleIron Uptake Oxidoreductase (IruO) Uses a Flavin Adenine Dinucleotide Semiquinone Intermediate for Iron-Siderophore Reduction.
Journal, issue, pagesACS Chem. Biol., Vol. 12, Page 1778-1786, Year 2017
Publish dateNov 12, 2016 (structure data deposition date)
AuthorsKobylarz, M.J. / Heieis, G.A. / Loutet, S.A. / Murphy, M.E.P.
External linksACS Chem. Biol. / PubMed:28463500
MethodsX-ray diffraction
Resolution1.822 - 2.31 Å
Structure data

PDB-5twb:
Oxidoreductase IruO in the reduced form
Method: X-RAY DIFFRACTION / Resolution: 1.822 Å

PDB-5twc:
Oxidoreductase IruO in the oxidized form
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (strain usa300) (bacteria)
KeywordsOXIDOREDUCTASE / siderophore / iron / flavin adenine dinucleotide

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