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Structure paper

TitleMolecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Journal, issue, pagesGenome Biol Evol, Vol. 9, Page 1212-1228, Year 2017
Publish dateFeb 24, 2017 (structure data deposition date)
Authorsde la Higuera, I. / Ferrer-Orta, C. / de Avila, A.I. / Perales, C. / Sierra, M. / Singh, K. / Sarafianos, S.G. / Dehouck, Y. / Bastolla, U. / Verdaguer, N. / Domingo, E.
External linksGenome Biol Evol / PubMed:28460010
MethodsX-ray diffraction
Resolution2.4 - 2.6 Å
Structure data

PDB-5n8x:
Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5n95:
Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-3PO:
TRIPHOSPHATE

Source
  • foot-and-mouth disease virus
KeywordsVIRAL PROTEIN / 3Dpolymerase / RNA dependent RNA polymerases / 5'-fluoracil / nucleotide analogues

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