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-Structure paper
Title | A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases. |
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Journal, issue, pages | ACS Chem. Biol., Vol. 12, Page 1499-1503, Year 2017 |
Publish date | Nov 30, 2016 (structure data deposition date) |
![]() | Kung, A. / Schimpl, M. / Ekanayake, A. / Chen, Y.C. / Overman, R. / Zhang, C. |
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Methods | X-ray diffraction |
Resolution | 2.14 - 2.23 Å |
Structure data | ![]() PDB-5mja: ![]() PDB-5mjb: |
Chemicals | ![]() ChemComp-7O3: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Receptor tyrosine kinase / kinase domain / Inhibitor / covalent |