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TitleCrystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
Journal, issue, pagesNat Commun, Vol. 8, Page 15024-15024, Year 2017
Publish dateJun 9, 2016 (structure data deposition date)
AuthorsKouno, T. / Silvas, T.V. / Hilbert, B.J. / Shandilya, S.M.D. / Bohn, M.F. / Kelch, B.A. / Royer, W.E. / Somasundaran, M. / Kurt Yilmaz, N. / Matsuo, H. / Schiffer, C.A.
External linksNat Commun / PubMed:28452355
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5keg:
Crystal structure of APOBEC3A in complex with a single-stranded DNA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / APOBEC3A / DNA cytidine deaminase complex with a substrate DNA / HYDROLASE-DNA complex

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