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TitleImmunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 9745-9759, Year 2017
Publish dateOct 17, 2016 (structure data deposition date)
AuthorsSkegro, D. / Stutz, C. / Ollier, R. / Svensson, E. / Wassmann, P. / Bourquin, F. / Monney, T. / Gn, S. / Blein, S.
External linksJ. Biol. Chem. / PubMed:28450393
MethodsX-ray diffraction
Resolution1.97 Å
Structure data

PDB-5m3v:
BEAT Fc
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody TCR Bispecific Interface

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