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-Structure paper
Title | Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 4093-4098, Year 2017 |
Publish date | Mar 21, 2017 (structure data deposition date) |
Authors | Morreale, F.E. / Bortoluzzi, A. / Chaugule, V.K. / Arkinson, C. / Walden, H. / Ciulli, A. |
External links | J. Med. Chem. / PubMed:28437106 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-5ngz: |
Chemicals | ChemComp-2BG: ChemComp-HOH: |
Source |
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Keywords | LIGASE / Ubiquitin-conjugating enzyme Ube2T / fragment screening / Fanconi anemia pathway / DNA repair |