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TitleCovalent Protein Labeling at Glutamic Acids.
Journal, issue, pagesCell Chem Biol, Vol. 24, Page 589-597.e5, Year 2017
Publish dateFeb 28, 2017 (structure data deposition date)
AuthorsMartin-Gago, P. / Fansa, E.K. / Winzker, M. / Murarka, S. / Janning, P. / Schultz-Fademrecht, C. / Baumann, M. / Wittinghofer, A. / Waldmann, H.
External linksCell Chem Biol / PubMed:28434875
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5nal:
The crystal structure of inhibitor-15 covalently bound to PDE6D
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-8RQ:
~{N}4-[(4-chlorophenyl)methyl]-~{N}1-(cyclohexylmethyl)-~{N}4-cyclopentyl-~{N}1-[(~{Z})-4-[(~{E})-methyliminomethyl]-5-oxidanyl-hex-4-enyl]benzene-1,4-disulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / Woodward's reagent K / Covalent Protein Labeling at Glutamic Acids / Arl2 mediated cargo release

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