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TitleCrystal structure of the C-terminal domain of Bacillus subtilis GabR reveals a closed conformation by gamma-aminobutyric acid binding, inducing transcriptional activation
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 487, Page 287-291, Year 2017
Publish dateJan 19, 2017 (structure data deposition date)
AuthorsPark, S.A. / Park, Y.S. / Lee, K.S.
External linksBiochem. Biophys. Res. Commun. / PubMed:28412355
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5x03:
Crystal structure of the C-terminal domain of Bacillus subtilis GabR reveals a closed conformation by the binding of gamma-aminobutyric acid, inducing the transcriptional activation
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-ABU:
GAMMA-AMINO-BUTANOIC ACID / neurotransmitter, inhibitor*YM

ChemComp-HOH:
WATER

Source
  • bacillus subtilis (strain 168) (bacteria)
KeywordsTRANSCRIPTION / Transcriptional regulator / Aminotransferase-like domain / External Schiff base

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