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Structure paper

TitleStructure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.
Journal, issue, pagesProtein Sci., Vol. 26, Page 1196-1205, Year 2017
Publish dateMar 10, 2017 (structure data deposition date)
AuthorsTerzyan, S.S. / Cook, P.F. / Heroux, A. / Hanigan, M.H.
External linksProtein Sci. / PubMed:28378915
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5v4q:
Crystal Structure of human GGT1 in complex with DON
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-8WY:
5,5-dihydroxy-L-norleucine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / NTN-HYDROLASE FAMILY / GLYCOPROTEIN / N- GLYCOSYLATION / CELL SURFACE / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex

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