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TitleCrystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 73, Page 340-348, Year 2017
Publish dateOct 6, 2016 (structure data deposition date)
AuthorsPidugu, L.S. / Neu, H. / Wong, T.L. / Pozharski, E. / Molloy, J.L. / Michel, S.L. / Toth, E.A.
External linksActa Crystallogr D Struct Biol / PubMed:28375145
MethodsX-ray diffraction
Resolution1.75 - 1.88 Å
Structure data

PDB-5tk5:
Crystal structure of human 3HAO with iron bound in the active site
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-5tkq:
Crystal structure of human 3HAO with zinc bound in the active site
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / 3-hydroxyanthranilate oxygenase dioxygenase / cupin kynurenine pathway / 3-hydroxyanthranilate oxygenase

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