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TitlePharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons.
Journal, issue, pagesJ. Pharmacol. Exp. Ther., Vol. 361, Page 355-365, Year 2017
Publish dateDec 14, 2016 (structure data deposition date)
AuthorsTraub, S. / Stahl, H. / Rosenbrock, H. / Simon, E. / Florin, L. / Hospach, L. / Horer, S. / Heilker, R.
External linksJ. Pharmacol. Exp. Ther. / PubMed:28351853
MethodsX-ray diffraction
Resolution2.594 Å
Structure data

PDB-5mo9:
Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20
Method: X-RAY DIFFRACTION / Resolution: 2.594 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Trk receptor / antibody / antigen / complex

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