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-Structure paper
Title | Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations. |
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Journal, issue, pages | Glycobiology, Vol. 27, Page 777-786, Year 2017 |
Publish date | Feb 22, 2017 (structure data deposition date) |
Authors | McMillan, B.J. / Zimmerman, B. / Egan, E.D. / Lofgren, M. / Xu, X. / Hesser, A. / Blacklow, S.C. |
External links | Glycobiology / PubMed:28334865 |
Methods | X-ray diffraction |
Resolution | 2.09 - 2.41 Å |
Structure data | PDB-5ux6: PDB-5uxh: |
Chemicals | ChemComp-NAG: ChemComp-GOL: ChemComp-HOH: ChemComp-GFB: |
Source |
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Keywords | TRANSFERASE / GDP-fucose / Notch signaling / POFUT1 / T-ALL |