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TitleSensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-kappa B Activation and Shapes a Proinflammatory Antibacterial State.
Journal, issue, pagesImmunity, Vol. 46, Page 433-445, Year 2017
Publish dateFeb 22, 2017 (structure data deposition date)
AuthorsMcFarland, A.P. / Luo, S. / Ahmed-Qadri, F. / Zuck, M. / Thayer, E.F. / Goo, Y.A. / Hybiske, K. / Tong, L. / Woodward, J.J.
External linksImmunity / PubMed:28329705
MethodsX-ray diffraction
Resolution1.501 Å
Structure data

PDB-5uxf:
Crystal Structure of mouse RECON (AKR1C13) in complex with Cyclic di-AMP
Method: X-RAY DIFFRACTION / Resolution: 1.501 Å

Chemicals

ChemComp-2BA:
(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / Cyclic di-AMP / Aldo-keto reductase / TIM barrel

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