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-Structure paper
Title | Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 2963-2972, Year 2017 |
Publish date | Nov 30, 2016 (structure data deposition date) |
![]() | Mpakali, A. / Saridakis, E. / Harlos, K. / Zhao, Y. / Kokkala, P. / Georgiadis, D. / Giastas, P. / Papakyriakou, A. / Stratikos, E. |
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Methods | X-ray diffraction |
Resolution | 2.53 Å |
Structure data | ![]() PDB-5mj6: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-ZN: ![]() ChemComp-7O2: ![]() ChemComp-BR: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / Insulin-regulated aminopeptidase / Endoplasmatic Reticulum Aminopeptidases / generation of antigenic peptides for cross-presentation / phosphinic pseudotripeptides / ligand-induced conformational changes |