Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structure-based discovery of LpxC inhibitors.
Journal, issue, pages	Bioorg. Med. Chem. Lett., Vol. 27, Page 1670-1680, Year 2017
Publish date	Feb 23, 2017 (structure data deposition date)
Authors	Zhang, J. / Chan, A. / Lippa, B. / Cross, J.B. / Liu, C. / Yin, N. / Romero, J.A. / Lawrence, J. / Heney, R. / Herradura, P. ...Zhang, J. / Chan, A. / Lippa, B. / Cross, J.B. / Liu, C. / Yin, N. / Romero, J.A. / Lawrence, J. / Heney, R. / Herradura, P. / Goss, J. / Clark, C. / Abel, C. / Zhang, Y. / Poutsiaka, K.M. / Epie, F. / Conrad, M. / Mahamoon, A. / Nguyen, K. / Chavan, A. / Clark, E. / Li, T.C. / Cheng, R.K. / Wood, M. / Andersen, O.A. / Brooks, M. / Kwong, J. / Barker, J. / Parr, I.B. / Gu, Y. / Ryan, M.D. / Coleman, S. / Metcalf, C.A.
External links	Bioorg. Med. Chem. Lett. / PubMed:28302397
Methods	X-ray diffraction
Resolution	1.9 Å
Structure data	PDB-5n8c: Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor Method: X-RAY DIFFRACTION / Resolution: 1.9 Å
Chemicals	ChemComp-ZN: Unknown entry ChemComp-8Q8: (2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide ChemComp-CL: Unknown entry ChemComp-HOH: WATER
Source	pseudomonas aeruginosa (bacteria)
Keywords	HYDROLASE / inhibitor / LpxC / hyroxamate / antibacterial