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Structure paper

TitleAntibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance.
Journal, issue, pagesMBio, Vol. 8, Year 2017
Publish dateMar 23, 2016 (structure data deposition date)
AuthorsEl-Halfawy, O.M. / Klett, J. / Ingram, R.J. / Loutet, S.A. / Murphy, M.E. / Martin-Santamaria, S. / Valvano, M.A.
External linksMBio / PubMed:28292982
MethodsX-ray diffraction
Resolution1.4 - 1.6 Å
Structure data

PDB-5ixg:
Crystal Structure of Burkholderia cenocepacia BcnB
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-5ixh:
Crystal Structure of Burkholderia cenocepacia BcnA
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-OTP:
(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • burkholderia cenocepacia pc184 (bacteria)
  • burkholderia cenocepacia bc7 (bacteria)
KeywordsUNKNOWN FUNCTION / beta barrel lipocalin

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