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TitleStructure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Journal, issue, pagesCell Host Microbe, Vol. 21, Page 403-414, Year 2017
Publish dateJan 31, 2017 (structure data deposition date)
AuthorsLennartz, F. / Adams, Y. / Bengtsson, A. / Olsen, R.W. / Turner, L. / Ndam, N.T. / Ecklu-Mensah, G. / Moussiliou, A. / Ofori, M.F. / Gamain, B. ...Lennartz, F. / Adams, Y. / Bengtsson, A. / Olsen, R.W. / Turner, L. / Ndam, N.T. / Ecklu-Mensah, G. / Moussiliou, A. / Ofori, M.F. / Gamain, B. / Lusingu, J.P. / Petersen, J.E. / Wang, C.W. / Nunes-Silva, S. / Jespersen, J.S. / Lau, C.K. / Theander, T.G. / Lavstsen, T. / Hviid, L. / Higgins, M.K. / Jensen, A.T.
External linksCell Host Microbe / PubMed:28279348
MethodsX-ray diffraction
Resolution2.78 Å
Structure data

PDB-5mza:
The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

Chemicals

ChemComp-3PO:
TRIPHOSPHATE

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-IHP:
INOSITOL HEXAKISPHOSPHATE

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum 3d7 (eukaryote)
  • homo sapiens (human)
KeywordsCELL ADHESION / PfEMP1 ICAM-1 Cerebral malaria

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