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Structure paper

TitleMechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-iota.
Journal, issue, pagesSci Rep, Vol. 7, Page 43904-43904, Year 2017
Publish dateJan 25, 2017 (structure data deposition date)
AuthorsJain, R. / Choudhury, J.R. / Buku, A. / Johnson, R.E. / Prakash, L. / Prakash, S. / Aggarwal, A.K.
External linksSci Rep / PubMed:28272441
MethodsX-ray diffraction
Resolution1.96 - 2.617 Å
Structure data

PDB-5ulw:
Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine
Method: X-RAY DIFFRACTION / Resolution: 2.617 Å

PDB-5ulx:
Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine crystallized in the presence of dCTP
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

Chemicals

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • unidentified (others)
KeywordsThansferase/DNA / human DNA polymerase iota N1-methyl-deoxyadenosine dTTP TLS / Thansferase-DNA complex / human DNA polymerase iota N1-methyl-deoxyadenosine dCTP TLS

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