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-Structure paper
Title | Multivalent Small-Molecule Pan-RAS Inhibitors. |
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Journal, issue, pages | Cell, Vol. 168, Page 878-889.e29, Year 2017 |
Publish date | Feb 8, 2017 (structure data deposition date) |
Authors | Welsch, M.E. / Kaplan, A. / Chambers, J.M. / Stokes, M.E. / Bos, P.H. / Zask, A. / Zhang, Y. / Sanchez-Martin, M. / Badgley, M.A. / Huang, C.S. ...Welsch, M.E. / Kaplan, A. / Chambers, J.M. / Stokes, M.E. / Bos, P.H. / Zask, A. / Zhang, Y. / Sanchez-Martin, M. / Badgley, M.A. / Huang, C.S. / Tran, T.H. / Akkiraju, H. / Brown, L.M. / Nandakumar, R. / Cremers, S. / Yang, W.S. / Tong, L. / Olive, K.P. / Ferrando, A. / Stockwell, B.R. |
External links | Cell / PubMed:28235199 |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.94 Å |
Structure data | PDB-5uqw: PDB-5us4: PDB-5usj: |
Chemicals | ChemComp-MG: ChemComp-GDP: ChemComp-HOH: ChemComp-GOL: ChemComp-GNP: |
Source |
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Keywords | HYDROLASE / KRAS / GTPase |