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Structure paper

TitleDirect evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 5970-5980, Year 2017
Publish dateOct 18, 2016 (structure data deposition date)
AuthorsDajnowicz, S. / Parks, J.M. / Hu, X. / Gesler, K. / Kovalevsky, A.Y. / Mueser, T.C.
External linksJ. Biol. Chem. / PubMed:28232482
MethodsX-ray diffraction
Resolution1.2 - 1.4 Å
Structure data

PDB-5ton:
Crystal structure of AAT H143L mutant
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-5toq:
High resolution crystal structure of AAT
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-5tor:
Crystal structure of AAT D222T mutant
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-5tot:
Crystal structure of AAT H143L:H189L double mutant
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • sus scrofa (pig)
KeywordsTRANSFERASE

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