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| Title | Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor. |
|---|---|
| Journal, issue, pages | J. Am. Chem. Soc., Vol. 139, Page 3528-3536, Year 2017 |
| Publish date | May 4, 2016 (structure data deposition date) |
Authors | Sanhueza, C.A. / Baksh, M.M. / Thuma, B. / Roy, M.D. / Dutta, S. / Preville, C. / Chrunyk, B.A. / Beaumont, K. / Dullea, R. / Ammirati, M. ...Sanhueza, C.A. / Baksh, M.M. / Thuma, B. / Roy, M.D. / Dutta, S. / Preville, C. / Chrunyk, B.A. / Beaumont, K. / Dullea, R. / Ammirati, M. / Liu, S. / Gebhard, D. / Finley, J.E. / Salatto, C.T. / King-Ahmad, A. / Stock, I. / Atkinson, K. / Reidich, B. / Lin, W. / Kumar, R. / Tu, M. / Menhaji-Klotz, E. / Price, D.A. / Liras, S. / Finn, M.G. / Mascitti, V. |
External links | J. Am. Chem. Soc. / PubMed:28230359 |
| Methods | X-ray diffraction |
| Resolution | 1.83 - 1.9 Å |
| Structure data | ![]() PDB-5jpv: ![]() PDB-5jq1: |
| Chemicals | ![]() ChemComp-CA: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-ZPF: |
| Source |
|
Keywords | SIGNALING PROTEIN / asialoglycoprotein receptor / carbohydrates / liver targeting / SUGAR BINDING PROTEIN |
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homo sapiens (human)
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