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Structure paper

TitleStructural insights into the activation mechanism of dynamin-like EHD ATPases.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 5629-5634, Year 2017
Publish dateJan 10, 2017 (structure data deposition date)
AuthorsMelo, A.A. / Hegde, B.G. / Shah, C. / Larsson, E. / Isas, J.M. / Kunz, S. / Lundmark, R. / Langen, R. / Daumke, O.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28228524
MethodsX-ray diffraction
Resolution2.79 - 3.268 Å
Structure data

PDB-5mtv:
Active structure of EHD4 complexed with ATP-gamma-S
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-5mvf:
Active structure of EHD4 complexed with ADP
Method: X-RAY DIFFRACTION / Resolution: 3.268 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • mus musculus (house mouse)
KeywordsENDOCYTOSIS / dynamin-like / membrane protein / auto-inhibition / activation

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