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Structure paper

TitleMechanism of partial agonism in AMPA-type glutamate receptors.
Journal, issue, pagesNat Commun, Vol. 8, Page 14327-14327, Year 2017
Publish dateApr 18, 2016 (structure data deposition date)
AuthorsSalazar, H. / Eibl, C. / Chebli, M. / Plested, A.
External linksNat Commun / PubMed:28211453
MethodsX-ray diffraction
Resolution1.229 Å
Structure data

PDB-5jei:
Crystal structure of the GluA2 LBD in complex with FW
Method: X-RAY DIFFRACTION / Resolution: 1.229 Å

Chemicals

ChemComp-FWD:
2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID

ChemComp-PO4:
PHOSPHATE ION

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-TOE:
2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL

ChemComp-PG0:
2-(2-METHOXYETHOXY)ETHANOL / inhibitor, precipitant*YM

ChemComp-ETE:
2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSPORT PROTEIN / ligand binding domain / glutamate receptor 2

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