Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Discovery of Novel, Orally Bioavailable beta-Amino Acid Azaindole Inhibitors of Influenza PB2.
Journal, issue, pages	ACS Med Chem Lett, Vol. 8, Page 256-260, Year 2017
Publish date	May 10, 2016 (structure data deposition date)
Authors	Farmer, L.J. / Clark, M.P. / Boyd, M.J. / Perola, E. / Jones, S.M. / Tsai, A. / Jacobs, M.D. / Bandarage, U.K. / Ledeboer, M.W. / Wang, T. ...Farmer, L.J. / Clark, M.P. / Boyd, M.J. / Perola, E. / Jones, S.M. / Tsai, A. / Jacobs, M.D. / Bandarage, U.K. / Ledeboer, M.W. / Wang, T. / Deng, H. / Ledford, B. / Gu, W. / Duffy, J.P. / Bethiel, R.S. / Shannon, D. / Byrn, R.A. / Leeman, J.R. / Rijnbrand, R. / Bennett, H.B. / O'Brien, C. / Memmott, C. / Nti-Addae, K. / Bennani, Y.L. / Charifson, P.S.
External links	ACS Med Chem Lett / PubMed:28197322
Methods	X-ray diffraction
Resolution	2.69 - 2.93 Å
Structure data	PDB-5jun: PB2 bound to an azaindole inhibitor Method: X-RAY DIFFRACTION / Resolution: 2.69 Å PDB-5jur: PB2 bound to an azaindole inhibitor Method: X-RAY DIFFRACTION / Resolution: 2.93 Å
Chemicals	ChemComp-6NU: (3~{R})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-3-(1-methylcyclobutyl)propanoic acid ChemComp-HOH: WATER ChemComp-6NS: (3~{R})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-4,4-dimethyl-pentanoic acid
Source	influenza a virus
Keywords	RNA BINDING PROTEIN / flu / polymerase / nucleotide binding / inhibitor