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-Structure paper
Title | Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 2018-2025, Year 2017 |
Publish date | Sep 7, 2016 (structure data deposition date) |
Authors | Gerlits, O. / Keen, D.A. / Blakeley, M.P. / Louis, J.M. / Weber, I.T. / Kovalevsky, A. |
External links | J. Med. Chem. / PubMed:28195728 |
Methods | neutron diffraction / X-ray diffraction |
Resolution | 1.85 Å |
Structure data | PDB-5t8h: |
Chemicals | ChemComp-478: ChemComp-DOD: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / aspartic protease drug resistant mutant amprenavir / HYDROLASE-HYDROLASE INHIBITOR complex |