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-Structure paper
| Title | Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2. |
|---|---|
| Journal, issue, pages | ACS Comb Sci, Vol. 19, Page 161-172, Year 2017 |
| Publish date | Nov 4, 2016 (structure data deposition date) |
Authors | Barnash, K.D. / The, J. / Norris-Drouin, J.L. / Cholensky, S.H. / Worley, B.M. / Li, F. / Stuckey, J.I. / Brown, P.J. / Vedadi, M. / Arrowsmith, C.H. ...Barnash, K.D. / The, J. / Norris-Drouin, J.L. / Cholensky, S.H. / Worley, B.M. / Li, F. / Stuckey, J.I. / Brown, P.J. / Vedadi, M. / Arrowsmith, C.H. / Frye, S.V. / James, L.I. |
External links | ACS Comb Sci / PubMed:28165227 |
| Methods | X-ray diffraction |
| Resolution | 1.74 Å |
| Structure data | ![]() PDB-5ttw: |
| Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-UNX: ![]() ChemComp-HOH: |
| Source |
|
Keywords | TRANSCRIPTION REGULATOR/INHIBITOR / WD40 / EED peptide inhibitor / TRANSCRIPTION REGULATOR-INHIBITOR complex |
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