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TitleCrystal Structure of an LSD-Bound Human Serotonin Receptor.
Journal, issue, pagesCell, Vol. 168, Page 377-389.e12, Year 2017
Publish dateNov 9, 2016 (structure data deposition date)
AuthorsWacker, D. / Wang, S. / McCorvy, J.D. / Betz, R.M. / Venkatakrishnan, A.J. / Levit, A. / Lansu, K. / Schools, Z.L. / Che, T. / Nichols, D.E. ...Wacker, D. / Wang, S. / McCorvy, J.D. / Betz, R.M. / Venkatakrishnan, A.J. / Levit, A. / Lansu, K. / Schools, Z.L. / Che, T. / Nichols, D.E. / Shoichet, B.K. / Dror, R.O. / Roth, B.L.
External linksCell / PubMed:28129538
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-5tvn:
Crystal structure of the LSD-bound 5-HT2B receptor
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-7LD:
(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide

ChemComp-CLR:
CHOLESTEROL

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
KeywordsMEMBRANE PROTEIN / LSD / GPCR / serotonin receptor

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