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Structure paper

TitleForce interacts with macromolecular structure in activation of TGF-beta.
Journal, issue, pagesNature, Vol. 542, Page 55-59, Year 2017
Publish dateDec 18, 2015 (structure data deposition date)
AuthorsDong, X. / Zhao, B. / Iacob, R.E. / Zhu, J. / Koksal, A.C. / Lu, C. / Engen, J.R. / Springer, T.A.
External linksNature / PubMed:28117447
MethodsX-ray diffraction
Resolution2.25 - 3.49 Å
Structure data

PDB-5ffg:
Crystal structure of integrin alpha V beta 6 head
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-5ffo:
Integrin alpha V beta 6 in complex with pro-TGF-beta
Method: X-RAY DIFFRACTION / Resolution: 3.49 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / integrin / TGF-beta

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