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-Structure paper
Title | Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library. |
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Journal, issue, pages | Chembiochem, Vol. 18, Page 864-871, Year 2017 |
Publish date | Dec 16, 2016 (structure data deposition date) |
Authors | Cuozzo, J.W. / Centrella, P.A. / Gikunju, D. / Habeshian, S. / Hupp, C.D. / Keefe, A.D. / Sigel, E.A. / Soutter, H.H. / Thomson, H.A. / Zhang, Y. / Clark, M.A. |
External links | Chembiochem / PubMed:28056160 |
Methods | X-ray diffraction |
Resolution | 1.33 Å |
Structure data | PDB-5u9d: |
Chemicals | ChemComp-83P: ChemComp-EDO: ChemComp-PEG: ChemComp-HOH: |
Source |
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Keywords | ANTITUMOR PROTEIN / Brutons tyrosine kinase / BTK / PROTEIN KINASE / DNA encoded library / PROTEROS BIOSTRUCTURES GMBH |