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TitleIntercalative DNA binding of the marine anticancer drug variolin B.
Journal, issue, pagesSci Rep, Vol. 7, Page 39680-39680, Year 2017
Publish dateSep 10, 2013 (structure data deposition date)
AuthorsCanals, A. / Arribas-Bosacoma, R. / Albericio, F. / Alvarez, M. / Aymami, J. / Coll, M.
External linksSci Rep / PubMed:28051169
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-4mnb:
Crystal Structure of a complex between the marine anticancer drug Variolin B and DNA
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-VAR:
9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-CO:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

KeywordsDNA / DNA duplex / Intercalation / Drug binding / Nucleus

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