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Structure paper

TitleStructural basis of an essential interaction between influenza polymerase and Pol II CTD.
Journal, issue, pagesNature, Vol. 541, Page 117-121, Year 2017
Publish dateOct 14, 2016 (structure data deposition date)
AuthorsLukarska, M. / Fournier, G. / Pflug, A. / Resa-Infante, P. / Reich, S. / Naffakh, N. / Cusack, S.
External linksNature / PubMed:28002402
MethodsX-ray diffraction
Resolution2.5 - 3.5 Å
Structure data

PDB-5m3h:
Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5m3j:
Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • influenza a virus
  • homo sapiens (human)
  • influenza b virus (b/memphis/13/2003)
  • influenza b virus
KeywordsTRANSFERASE / influenza RNA-dependent RNA polymerase / vRNA promoter / Pol II serine 5 phosphorylated CTD peptide / VIRAL PROTEIN / influenza B virus RNA-dependent RNA polymerase

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