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TitleReceptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
Journal, issue, pagesPLoS Pathog., Vol. 12, Page e1006098-e1006098, Year 2016
Publish dateJun 1, 2016 (structure data deposition date)
AuthorsKhasnis, M.D. / Halkidis, K. / Bhardwaj, A. / Root, M.J.
External linksPLoS Pathog. / PubMed:27992602
MethodsX-ray diffraction
Resolution1.8 - 1.85 Å
Structure data

PDB-5ka5:
HIV-1 gp41 variant V549E resistance mutation
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5ka6:
HIV-1 gp41 variant Q552R and L555M resistance mutations
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1
KeywordsVIRAL PROTEIN / Hiv-1 / membrane fusion / 5-helix / C-peptide / MEMBRANE PROTEIN

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