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Structure paper

TitleStructural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 24, Page 131-139, Year 2017
Publish dateAug 9, 2016 (structure data deposition date)
AuthorsShi, K. / Carpenter, M.A. / Banerjee, S. / Shaban, N.M. / Kurahashi, K. / Salamango, D.J. / McCann, J.L. / Starrett, G.J. / Duffy, J.V. / Demir, O. ...Shi, K. / Carpenter, M.A. / Banerjee, S. / Shaban, N.M. / Kurahashi, K. / Salamango, D.J. / McCann, J.L. / Starrett, G.J. / Duffy, J.V. / Demir, O. / Amaro, R.E. / Harki, D.A. / Harris, R.S. / Aihara, H.
External linksNat. Struct. Mol. Biol. / PubMed:27991903
MethodsX-ray diffraction
Resolution1.718 - 3.151 Å
Structure data

PDB-5sww:
Crystal Structure of Human APOBEC3A complexed with ssDNA
Method: X-RAY DIFFRACTION / Resolution: 3.151 Å

PDB-5td5:
Crystal Structure of Human APOBEC3B variant complexed with ssDNA
Method: X-RAY DIFFRACTION / Resolution: 1.718 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-IOD:
IODIDE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHydrolase/DNA / APOBEC3A / Cytidine deaminase / Hydrolase-DNA complex / Deaminase / DNA substrate complex

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