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Structure paper

TitleStructure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance.
Journal, issue, pagesPLoS Pathog., Vol. 12, Page e1006067-e1006067, Year 2016
Publish dateNov 21, 2016 (structure data deposition date)
AuthorsSobhanifar, S. / Worrall, L.J. / King, D.T. / Wasney, G.A. / Baumann, L. / Gale, R.T. / Nosella, M. / Brown, E.D. / Withers, S.G. / Strynadka, N.C.
External linksPLoS Pathog. / PubMed:27973583
MethodsX-ray diffraction
Resolution1.9 - 4 Å
Structure data

PDB-5tz8:
Crystal structure of S. aureus TarS
Method: X-RAY DIFFRACTION / Resolution: 4 Å

PDB-5tze:
Crystal structure of S. aureus TarS in complex with UDP-GlcNAc
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

PDB-5tzi:
Crystal structure of S. aureus TarS 1-349
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5tzj:
Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5tzk:
Crystal structure of S. aureus TarS 1-349 in complex with UDP
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

PDB-5u02:
Crystal structure of S. aureus TarS 217-571
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-UD1:
URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE

ChemComp-HOH:
WATER

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-IMD:
IMIDAZOLE

Source
  • staphylococcus aureus (bacteria)
KeywordsTRANSFERASE / Glycosyltransferase / GT-A / Wall teichoic acid

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