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-Structure paper
Title | Synthesis and Biological Evaluation of New Triazolo- and Imidazolopyridine ROR gamma t Inverse Agonists. |
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Journal, issue, pages | ChemMedChem, Vol. 11, Page 2640-2648, Year 2016 |
Publish date | Oct 31, 2016 (structure data deposition date) |
![]() | Hintermann, S. / Guntermann, C. / Mattes, H. / Carcache, D.A. / Wagner, J. / Vulpetti, A. / Billich, A. / Dawson, J. / Kaupmann, K. / Kallen, J. ...Hintermann, S. / Guntermann, C. / Mattes, H. / Carcache, D.A. / Wagner, J. / Vulpetti, A. / Billich, A. / Dawson, J. / Kaupmann, K. / Kallen, J. / Stringer, R. / Orain, D. |
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Methods | X-ray diffraction |
Resolution | 1.77 Å |
Structure data | ![]() PDB-5m96: |
Chemicals | ![]() ChemComp-Q6Y: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / nuclear hormone receptor / ligand-binding domain / inverse agonist |